Artem Pliss, PhD

Dr. Pliss has joined D’Youville University School of Pharmacy as an Assistant Professor in January 2024. Prior to that he worked as research faculty at the University at Buffalo.

• B.S./M.S. in Cell Biology and Histology, Taras Shevchenko National University, Kyiv, Ukraine, 1993
• Ph.D. in Cell Biology and Pathology; Charles University, Prague, Czech Republic, 2001

Dr. Pliss specializes broadly in cell and molecular biology, and advanced microscopy. His research is focused on the molecular environments in major cellular organelles and their transformations throughout cellular growth, disease progression or drug-cell interactions. Dr. Pliss also participates in the development of nanophotonics technologies for biomedical research.

Selected Publications:

• Pliss A, Kuzmin AN, Prasad PN and Mahajan SD. Mitochondrial dysfunction a prelude to neuro-pathogenesis of SARS-CoV-2. ACS Chemical Neuroscience (2022) 13: 308–312.

• Levchenko SM, Pliss A, Peng X, Prasad PN, Qu J. Fluorescence lifetime imaging for studying DNA compaction and gene activities. Light: Science & Applications. (2021) 10: 1-11.

• Pliss A, Kuzmin A, Lita A, Kumar R, Celiku O, Atilla-Gokcumen EG, Gokcumen O, Chandra D, Larion M, Prasad PN. Single organelle optical omics platform for cell science and biomarkers discovery. Analytical Chemistry (2021) 93: 8281–8290.

• Lita A, Pliss A, Kuzmin A, Yamasaki T, Zhang L, Dowdy T, Burks C, de Val N, Celiku O, Ruiz-Rodado V, Nicoli ER, Kruhlak M, Andresson T, Das S, Yang C, Schmitt R, Herold-Mende C, Gilbert M, Prasad PN. IDH1 Mutations Induce Organelle Defects via Dysregulated Phospholipids. Nature Communications, (2021) 12:614

• Pliss A and Prasad PN. High resolution mapping of subcellular refractive index by fluorescence lifetime imaging: a next frontier in quantitative cell science? Methods Appl Fluores. (2020) 8(3). doi: 10.1088/2050-6120/ab8571.

• Pliss A, Levchenko SM, Liu L, Peng X, Ohulchanskyy TY, Roy I, Kuzmin AN, Qu J, Prasad PN. Cycles of protein condensation and discharge in nuclear organelles studied by fluorescence lifetime imaging. Nature Communications, (2019) 10:455.

• Pliss A, Ohulchanskyy TY, Chen G, Damasco J, Bass C and Prasad PN. Subcellular Optogenetics Enacted by Targeted Nanotransformers of Near-Infrared Light. ACS Photonics, (2017) 4: 806–814.

• Pliss A, Peng X, Liu L, Kuzmin A, Wang Y, Qu J, Li Y, and Prasad PN. Single Cell Assay for Molecular Diagnostics and Medicine: Monitoring Intracellular Concentrations of Macromolecules by Two-Photon Fluorescence Lifetime Imaging. Theranostics, (2015) 5: 919-930.

• Pliss A, Kuzmin A, Kachynski AV, Baev A, Berezney R and Prasad PN. Fluctuations and Synchrony of RNA Synthesis in Nucleoli. Integrative Biology (2015) 7: 681- 692.

• Yadav N, Pliss A, Kuzmin AN, Rapal P, Sun L, Prasad PN, and Chandra D. Transformations of the Macromolecular Landscape at Mitochondria During DNA-Damage Induced Apoptotic Cell Death. Cell Death & Disease, (2014) 5: e1453.

Link to Google Scholar Profile: https://scholar.google.com/citations?user=9zlAKM4AAAAJ&hl=en&oi=ao