Jason Den Haese, BS, MS

I have a strong and diverse research background acquired from experience in industry, clinical, and academic settings. I was the director of gene cloning and research at IMMCO Diagnostics Company where I used my training in molecular biology, microbiology, immunology, and biochemistry to produce 2 new products for diagnosing autoimmune disease in patients in just under three years. In a clinical research setting, I spent 13 years working at Roswell Park Comprehensive Cancer Center (RPCCC) focusing on cancer prevention and leukemia. In an academic setting, I collaborated and published with several of my peers and students at D’Youville University and RPCCC. In 2020, I continued to expand my research acumen by starting my research program at DYU working with fish from the armored catfish families of the Amazon River Basin. My passion for research is only rivaled by my passion for teaching and service to others. I am particularly passionate about mentoring and have dedicated much of my time creating supportive and engaging environments for my students both the classroom and the wider community. I strongly believe in giving back to those in need and am actively involved in volunteering within the university and the greater community.

• M.S., Biology, Oncology, Niagara University and Roswell Park Cancer Institute, 1991-1993
• B.S., Biochemistry, Niagara University, 1987-1991

• Teaching Excellence Recognition by D'Youville University Women’s Soccer Team (2022)
• Teaching Excellence Recognition by D'Youville University Men’s Soccer Team (2022)
• Faculty Member of the Year in the Biology and Mathematics Department (2020)
• Faculty Mentor to D’Youville University Women’s Soccer team (2019)
• Influential Person Award by Allegany County Area Foundation (2016)
• Faculty Member of the Year at D’Youville University (2016)
• Excellence Award from the Buffalo Academy of Science Charter School (2016)
• D’Youville University Professor of the Month (April 2016)
• M & T Bank/Buffalo Bills Touchdown for Teachers (2014)
• D’Youville University Professor of the Month (October 2013)

My current research focus has two major aims, understanding the growth and survival of fry from the armored catfish families from South America and conservation of fish from the armored catfish family that threatened in the wild.

• Elmeliegy, M, Den Haese, J, Talati, C, Weytzler, M and Jusko, WJ. Optimizing Combination Regimens of Cytarabine and FLT3 Inhibitors in Acute Myeloid Leukemia. Cancer Chemotherapy and Pharmacology (2020) 86:325-337.
• Gerace, MM, Den Haese, JP, Bakin, AV and Gervasi, ME. Transforming Growth Factor Beta (TGF-β) Suppresses Inflammation Through the Repression of Interleukin-33 (IL-33) FASEB J., 2018.  32(1): 509.4.
• Woelfel, J, Den Haese, J, Gervasi, ME, and Ruvio, S.  Regulation of Interleukin 33 by Transforming Growth Factor-β in Epithelia Cells, Fibroblasts and Keratinocytes.  FASEB J., 2017.  31(1): 908.11.
• Nourkeyhani H., Den Haese J., Portwood S., Hanekamp D., Johnson M., and Wang E. Targeting Autophagy as a Therapeutic Strategy in Acute Myeloid Leukemia. Blood; 2016 128:3950.
• Przespolewski A., Portwood S., Den Haese J., Lewis, D., and Wang E. Targeting Innate and Adaptive Immune Responses for the Treatment of Acute Myeloid Leukemia. Blood; 2016 128:2833.
• Hurley, M; Lee, WY; Beyea, H; Den Haese, J; Stevens, T; Olivieri, MP. “Variations in the Branching of the Lingual and Facial Arteries.”  FASEB J. 2016; 30:779.20.
• Frangou, C., Den Haese, J., Nowak, N., Johnson, C., Trump, D., and Wetzler, M. 25(OH) Vitamin D3 Affects Acute Myeloid Leukemia Cell Proliferation. Blood. 2013;122;5026
• Den Haese, J., Frangou,C., Johnson, C., Trump, D.,and  Wetzler M. 25(OH) Vitamin D3 Delays Leukemogenesis in an Acute Myeloid Leukemia Murine Model.  Society of Hematologic Oncology (SOHO) Annual Meeting, September 18-21, 2013, Houston, Texas. Poster #209.  
• Thudium KE, Ghoshal S, Fetterly, Gerald J, Den Haese, J., Karpf, Adam R, Wetzler, Meir. Leukemia Research 2012 36(11):1410-16.  Synergism between clofarabine and decitabine through p53R2: A pharmacodynamics drug-drug interaction modeling.
• Bousman CA, Rivard C, Den Haese, J., Ambrosone C, Hyland A.  Am J Med Genet B Neuropsychiatr Genet. 2012 Mar; 159B (2):227-35. 2012 Jan 5. Alpha-5 and -3 nicotinic receptor gene variants predict nicotine dependence but not cessation: findings from the COMMIT cohort.