Mudit Singhal, PhD

Dr. Singhal joined D'Youville University as an Assistant Professor in the School of Pharmacy, Department of Pharmaceutical, Social and Administrative Sciences, in 2010 and was promoted to Associate Professor in 2016. His teaching interests include courses in medicinal chemistry, natural products, and contemporary pharmacy compounding and calculations. Dr. Singhal earned his doctorate degree in pharmaceutical sciences from the University of Louisiana at Monroe (ULM). He is an active member of several professional organizations, including the American Association of Colleges of Pharmacy, the American Association of Pharmaceutical Scientists (AAPS), and the American Chemical Society. He has given numerous research presentations at both regional and national meetings and has been recognized by the AAPS for excellence in graduate education in the fields of Drug Design and Discovery. He has also been a reviewer for many scientific manuscripts, research and educational grants, and annual professional meeting abstracts and posters.

• PhD Pharmaceutical Sciences, University of Louisiana at Monroe
• BS Pharmacy, Dr. Harisingh Gour University

Dr. Singhal’s research primarily involves both the discovery and development of effective therapeutic agents that originate either from natural products or synthetic scaffolds. In addition, as an enthusiastic proponent of quality assurance for marketed products, Dr. Singhal constantly evaluates the quality of dietary supplements and miscellaneous student-compounded, non-sterile products. The scholarship of teaching is something that Dr. Singhal values; therefore, he regularly experiments with new active learning strategies, such as educational gaming, and incorporates them into his pharmacy-related courses.

• Singhal M. Facilitating virtual medicinal chemistry active learning assignments using advanced Zoom features during COVID-19 campus closure. J. Chem. Educ. 2020, 97, 2711-2714.
• Seo S, Ombengi D, Sultan D, Kahaleh A, Nonyel N, Karwa R, Abrons J, Lukas S, Singhal M, Miller M, Truong H. An ethics-based approach to global health research part 1: Building partnerships in global health. Res Social Adm Pharm. 2020, 16, 1574-1579.
• Lukas S, Crowe S, Law M, Kahaleh A, Addo-Atuah J, Nonyel N, Ombengi, D, Singhal M, Sultan D, Tamukong R. An ethics-based approach to global health research part 2: Strategies for overcoming logistic and implementation challenges. Res Social Adm Pharm. 2020, 16, 1580-1587.
• Mudit M, Alfonso LF. Analytical evaluation of the accuracy and retention of compounding skills among PharmD students. Am J Pharm Educ. 2017, 81, 1-6.
• Palem JR, Mudit M, Hsia SV, El Sayed KA. Discovery and preliminary structure-activity relationship of the marine natural product manzamines as herpes simplex virus type-1 inhibitors. Z Naturforsch C. 2017, 72, 49-54.
• Mudit M, El Sayed KA. Cancer control potential of marine natural product scaffolds through inhibition of tumor cell migration and invasion. Drug Discov Today. 2016, 21, 1745-1760.
• Mudit M, Samant GV. Computer-aided drug design. The Sage Encyclopedia of Pharmacology and Society, Boslaugh SE (editors), Thousand Oaks, CA, 2015.
• Mudit M, El Sayed KA. Optimization of (phenylmethylidene)-hydantoins as prostate cancer migration inhibitors: SAR-directed design, synthesis, and pharmacophore modeling. Chem Biodivers. 2011, 8, 1470-1485.
• Mudit M, Khanfar M, Shah GV, El Sayed KA. Methods for evaluation of structural and biological properties of anti-invasive natural products. Methods in Molecular Biology: Drug Design and Discovery Issue, Humana Press, NY, 2011, 716, 55-71. (Book Chapter)
• Mudit M, Behery FA, Wali VB, Sylvester PW, El Sayed KA. Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and -tocotrienol. Nat Prod Commun. 2010, 5, 1623-1626.
• Mudit M, Khanfar M, Muralidharan A, Thomas S, Shah GV, El Sayed KA. Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products. Bioorg Med Chem. 2009, 17, 1531-1538.
• Shah GV, Muralidharan A, Thomas S, Gokulgandhi M, Mudit M, Khanfar M, El Sayed KA. Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis. Mol Cancer Ther. 2009, 8, 509-520.